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A messenger ribonucleic acid (mRNA) comprising an open reading frame (ORF) that encodes at least two domains of a SARS-CoV-2 Spike protein, and less than the full length spike protein. 2. The mRNA of claim 1, wherein one of the two domains is an N-terminal domain (NTD) of a SARS-CoV-2 Spike protein. 3.an assay is used to determine whether the patient has KRas G12D mutation using a sample (e.g., a biological sample or a biopsy sample (e.g., a paraffin-embedded biopsy sample) from a patient (e.g., a patient suspected of having a KRas G12D-associated cancer, a patient having one or more symptoms of a KRas G12D-associated cancer, and/or a …This application claims the benefit of U.S. Provisional Patent Application Serial No. 61/975,601 , filed April 4, 2014, entitled "Systems and Methods for Injectable Devices," incorporated herein by reference in its entirety. GOVERNMENT FUNDING. This invention was made with government support under Grant No.One embodiment of the present subject matter includes a cushion including a case containing a filling of foam pieces, the filling made by the process of feeding a foam block into a cutting machine; cutting the foam block with the cutting machine; collecting a first plurality of foam pieces with an approximately 0.375 inch to an approximately 0.625 inch …In one particular embodiment, LAG-3 positive or LAG-3 expression positive tumor means that at least about 1%, or in the range of 1- 5% of the total number of tumor-infiltrating inflammatory cells (e.g., T cells, CD8+ T cells, CD4+ T cells, FOXP3+ cells) express LAG-3 on the cell surface.

The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Google will consider licensing offers for granted patents. If you do not have a patent but only a business idea, please do not make a submission as we will not consider non …A slide-stopacuated by the magazine-follower to arrest the breech-slide in the open position when the magazine is empty,'has beenheretofore described and shown in the United States Patent- No. 708794, granted to me September 9, 1902, but the construction of the slide-stop as an integral part of the handle of the pivot-pin securing "the barrel and the breech …

We would like to show you a description here but the site won’t allow us.A system and method causes a computer to detect and perform actions on structures identified in computer data. The system provides an analyzer server, an application program interface, a user interface and an action processor. The analyzer server receives from an application running concurrently data having recognizable structures, uses a pattern …

SUMMARY OF THE INVENTION [0007] In one aspect of the invention, compounds are provided that inhibit KRas G12D activity. In certain embodiments, the compounds are represented by Formula (I): Formula (I) [0008] or a pharmaceutically acceptable salt thereof: [0009] wherein: [00010] R 1 is hydrogen, hydroxy, halogen, C1 – C3 alkyl, C1 - C3 ... This patent search tool allows you not only to search the PCT database of about 2 million International Applications but also the worldwide patent collections. This search facility features: flexible search syntax; automatic word stemming and relevance ranking; as well as graphical results. Abstract. A spacecraft having a triangular hull with vertical electrostatic line charges on each corner that produce a horizontal electric field parallel to the sides of the hull. This field, interacting with a plane wave emitted by antennas on the side of the hull, generates a force per volume combining both lift and propulsion. About Google Patents. Overview. Search and read the full text of patents from around the world. Next: Coverage. Patents from around the world, translated. Plus technical papers … Google's Patent Opportunity Submission Portal. Google will consider licensing offers for granted patents submitted through this portal.

WW/LGOOGO fhweutoz we umloxu. umcmm wm co: AAAAAA v, UNITED STATES PATENT OFFICE. NIKOLA TESLA, OF NEIV YORK, N. Y. ELECTRIC G EN ERATO R. SPECIFICATION forming part of Letters Patent No. 511,916, dated January 2, 1894. Application filed August 19,1893.

1. Start with a simple keyword search. Go to patents.google.com and enter the keywords in the search bar. Example query: oral care. This will returns patents …

USD504889S1 US29/201,636 US20163604F USD504889S US D504889 S1 USD504889 S1 US D504889S1 US 20163604 F US20163604 F US 20163604F US D504889 S USD504889 S US D504889S Authority US United States Prior art keywords electronic device view ornamental design design perspective Prior art date 2004-03-17 Legal … The vaccine is an ultimate weapon for eliminating major infectious diseases, has the advantages of lowest cost and more advantages of prior enemy than other therapies, undoubtedly becomes hopeful to the public, the smallpox is eliminated by human beings through vaccination, the poliomyelitis cases are reduced by 99 percent, the infectious diseases such as diphtheria are rare, and the incidence ... 3-D diamond printing using a pre-ceramic polymer with a nanoparticle filler. JP2015171780A ( en ) *. 2014-03-12. 2015-10-01. セイコーエプソン株式会社. Method for manufacturing three-dimensional molded article, apparatus for manufacturing three-dimensional molded article, and three-dimensional molded article.Google Patents organizes the world's inventions to make them universally accessible and useful. As part of this goal, Google has machine-annotated the worldwide …Abstract. The invention provides for application of Salicylic Acid, in proportion and concentration depending upon the size of cancer, onto or into a cancerous area in the body, in order to reduce and remove the cancer. Upon application, Salicylic Acid will destroy all the extra cells in the body that form cancer and rid the body of cancer.

US2082748A 1937-06-01 Combined socket and slotted screw. US3108623A 1963-10-29 Tools for recessed head fasteners. US2046840A 1936-07-07 Screw driver. US2046839A 1936-07-07 Screw. US3237506A 1966-03-01 Recessed head fasteners. US2046343A 1936-07-07 Screw. US2066484A 1937-01-05 Screw. US1910182A 1933-05-23 Slotted socket … Search within the title, abstract, claims, or full patent document: You can restrict your search to a specific field using field names.. Use TI= to search in the title, AB= for the abstract, CL ... Abstract. Free Energy is a perpetual motion machine that operates indefinitely and independently without any other source of fuel, electricity, or any other renewable energy source other than gravity. Free Energy produces more energy than the amount of energy necessary to operate the machine itself. Never before has a machine …Мы хотели бы показать здесь описание, но сайт, который вы просматриваете, этого не позволяет.Abstract. A spacecraft having a triangular hull with vertical electrostatic line charges on each corner that produce a horizontal electric field parallel to the sides of the hull. This field, interacting with a plane wave emitted by antennas on the side of the hull, generates a force per volume combining both lift and propulsion.Mar 28, 2024 · What is Google Patents. Google Patents is Google's own patent search tool. It draws on patents from more than 100 of the biggest patent offices from around the world, enabling you to search across more than 120 million documents. As such it rivals the EPO's Espacenet for coverage. Full-text patent documents are indexed from 20 of the biggest ... Мы хотели бы показать здесь описание, но сайт, который вы просматриваете, этого не позволяет.

2005-08-01 FPAY Fee payment. Year of fee payment: 12. The invention provides improved methods for assaying samples for the presence of a beetle luciferase. The methods of the invention entail improved kinetics of light production from luciferase activity in beetle luciferase-luciferin reactions.This is Google's portal for receiving patent opportunities. To submit a patent opportunity, please click here. All requests must be submitted in English. Google's Patent Opportunity...

Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 2016-03-01 Filing date 2016-03-01 Publication date 2016-12-29 ... J. S. (2015). Thermodynamic model of a nervous system US Patent No. 2015/0379898 A1; Goldberg, J. S. (2016). Method to optimize electrode placement for …2005-08-01 FPAY Fee payment. Year of fee payment: 12. The invention provides improved methods for assaying samples for the presence of a beetle luciferase. The methods of the invention entail improved kinetics of light production from luciferase activity in beetle luciferase-luciferin reactions. Google Patents, a patent search engine created by Google, includes over 120 million patent publications from 100+ patent offices around the world, as well as many technical documents and books indexed in Google Scholar and Google Books. It currently indexes full-text documents from the following Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 2014-05-28 Filing date 2015-05-27 Publication date 2016-07-19 2014-10-02 Priority claimed from US14/505,478 external-priority patent/US9537811B2/en 2015-05-27 Priority to US14/723,400 priority Critical patent/US9396354B1/enМы хотели бы показать здесь описание, но сайт, который вы просматриваете, этого не позволяет.Mar 19, 2019 · The Basics of Google Patent Search. First, there’s no universal “best” way to perform a Google patent search. That said, this article will outline how we approach patent searches—which happens to be the best way to start. Note the checkbox beneath the search menu. Check that if you want to include non-patent literature in your search. Mar 28, 2024 · Google patents database is built using patents from 17 patent offices* around the world. The database contains over 87 million patent publications including. Search Techniques. You can directly type text in the search bar. The search engine splits search strings and searches individual keywords in the search string. Oct 18, 2018 · Public Search Facility. The United States Patent and Trademark Office (USPTO) Public Search Facility located in Alexandria, VA provides the public access to patent and trademark information in a variety of formats including on-line, microfilm, and print. Trained staff are available to assist public users. Publication Publication Date Title. US6468525B1 2002-10-22 Probiotic formulation. TWI574633B 2017-03-21 Compositions comprising probiotic and prebiotic components and mineral salts, with lactoferrin. US8404228B2 2013-03-26 Food containing a probiotic and an isolated β-glucan and methods of use thereof.

WW/LGOOGO fhweutoz we umloxu. umcmm wm co: AAAAAA v, UNITED STATES PATENT OFFICE. NIKOLA TESLA, OF NEIV YORK, N. Y. ELECTRIC G EN ERATO R. SPECIFICATION forming part of Letters Patent No. 511,916, dated January 2, 1894. Application filed August 19,1893.

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JP2016523981A5 - - Google Patents. Other languages. English. Worldwide applications. 2014 PT CA WO EP BR RS JP HU CN SI US ES AU EP PL DK LT 2016 IL 2018 US US 2020 US 2021 CY HR 2023 US. Application JP2016525813A events. 2013-08-13. Priority claimed from US13/966,229. 2014-07-11.Abstract. Free Energy is a perpetual motion machine that operates indefinitely and independently without any other source of fuel, electricity, or any other renewable energy source other than gravity. Free Energy produces more energy than the amount of energy necessary to operate the machine itself. Never before has a machine …Patent: A patent is a government license that gives the holder exclusive rights to a process, design or new invention for a designated period of time. Applications for patents are usually handled ...The device of claim 1, further comprising a compressed gas source within the container and piped to release compressed gas within the mosquito breeding bin. US14/549,3052014-11-202014-11-20Toxic mosquito aerial release system ActiveUS8967029B1(en) Priority Applications (1) Application Number.2005-08-30. Method and apparatus for personalized conference and hands-free telephony using audio beaming. US11082763B2 ( en ) 2021-08-03. Handheld acoustic hailing and disruption systems and methods. US20170148466A1 ( en ) 2017-05-25. Method and system for reducing background sounds in a noisy environment.About Google Patents. Coverage. Next: Searching. Google Patents includes over 120 million patent publications from 100+ patent offices around the world, as well as many …2. A coil composed'of contiguous or adjacent insulated conductors electrically con; nected in seriesand having a potential ditference of such value as to give to the coil as a whole, a capacity sufficient to neutralize its self-induction, as set forth. NIKOLA TESLA. ` …Additional advanced tip – Google Patents also includes the capability of searching non-patent literature using all the tips and tricks mentioned above. A user may simply select the “Scholar” look-alike logo to include the non-patent literature (the “Bulb” look-alike logo is to search the patent literature ).2. A coil composed'of contiguous or adjacent insulated conductors electrically con; nected in seriesand having a potential ditference of such value as to give to the coil as a whole, a capacity sufficient to neutralize its self-induction, as set forth. NIKOLA TESLA. ` … The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors.

The vaccine is an ultimate weapon for eliminating major infectious diseases, has the advantages of lowest cost and more advantages of prior enemy than other therapies, undoubtedly becomes hopeful to the public, the smallpox is eliminated by human beings through vaccination, the poliomyelitis cases are reduced by 99 percent, the infectious diseases such as diphtheria are rare, and the incidence ... Publication Publication Date Title. US1773079A 1930-08-12 Method of preparing food products. US1810864A 1931-06-16 Process for the production of food product bricks. US2286644A 1942-06-16 Method and apparatus for processing potatoes. US1998431A 1935-04-23 Method and apparatus for freezing food products.3-D diamond printing using a pre-ceramic polymer with a nanoparticle filler. JP2015171780A ( en ) *. 2014-03-12. 2015-10-01. セイコーエプソン株式会社. Method for manufacturing three-dimensional molded article, apparatus for manufacturing three-dimensional molded article, and three-dimensional molded article. Publication Publication Date Title. US3951134A 1976-04-20 Apparatus and method for remotely monitoring and altering brain waves. US5458123A 1995-10-17 System for monitoring patient location and data. US3603881A 1971-09-07 Frequency shift telemetry system with both radio and wire transmission paths. Instagram:https://instagram. movies play complane ticket san jose to laigfollowfreezenova.games Search by application number, patent number, PCT number, publication number or international design registration number. Application # All fields. Application # Patent # PCT # Publication # Intl. Design Reg. # search. Receive updates from the USPTO. Enter your email to subscribe or update your preferences. seattle to san diego flightpassportparking com Mar 19, 2019 · The Basics of Google Patent Search. First, there’s no universal “best” way to perform a Google patent search. That said, this article will outline how we approach patent searches—which happens to be the best way to start. Note the checkbox beneath the search menu. Check that if you want to include non-patent literature in your search. First worldwide family litigation filed. 2013-12-16. Priority to US14/106,988. 2013-12-16. Application filed by Moderna Therapeutics Inc. 2014-04-17. Publication of US20140107189A1. 2016-04-05. Publication of US9301993B2. nyu langone medical center my chart Oct 3, 2022 · Additional advanced tip – Google Patents also includes the capability of searching non-patent literature using all the tips and tricks mentioned above. A user may simply select the “Scholar” look-alike logo to include the non-patent literature (the “Bulb” look-alike logo is to search the patent literature ). Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 1996-12-13 Filing date 2002-04-24 Publication date 2003-07-01 ... 2002-09-05 Publication of US20020123775A1 publication Critical patent/US20020123775A1/en 2003-07-01 Application granted granted Critical SUMMARY OF THE INVENTION [0007] In one aspect of the invention, compounds are provided that inhibit KRas G12D activity. In certain embodiments, the compounds are represented by Formula (I): Formula (I) [0008] or a pharmaceutically acceptable salt thereof: [0009] wherein: [00010] R 1 is hydrogen, hydroxy, halogen, C1 – C3 alkyl, C1 - C3 ...